| 摘要 |
A 7???-methoxycephalosporin represented by the following general formula and a salt thereof: <IMAGE> wherein R<1> represents a hydrogen atom or a carboxyl-protecting group; R<2> represents an organic group linked to the carbon atom through an oxygen or sulfur atom; R<3> represents a lower alkyl group; n is 0, 1 or 2; A represents a substituted or unsubstituted alkyl group; R<4> represents a lower alkyl group; and R<5> represents a hydrogen atom or a hydroxyl-protecting group, have a broad antibacterial spectrum and high resistance to ???-lactamase produced from bacteria, and are well absorbed in a living body. They can be incorporated into pharmaceutical compositions. |
