发明名称 |
Preparations of purified bacterial membranal proteoglycans |
摘要 |
This invention relates to a process for the preparation of purified bacterial membranal proteoglycans. The process comprises at least one step in which crude proteoglycans are treated in aqueous medium with a base or a hypobromite, followed by elimination of the excess reactant and the insoluble residue, the purified proteoglycans being present in aqueous solution. The thus obtained purified proteoglycans may be used as immunity adjuvants in vaccines without causing side-effects such as pyrogenic reactions. |
申请公布号 |
US4397838(A) |
申请公布日期 |
1983.08.09 |
申请号 |
US19810280379 |
申请日期 |
1981.07.06 |
申请人 |
PIERRE FABRE S.A. |
发明人 |
D'HINTERLAND, LUCIEN D.;NORMIER, GERARD;PINEL, ANNE-MARIE;DURAND, JACQUES |
分类号 |
A61K35/74;A61K39/02;A61K39/05;A61K39/07;A61K39/085;A61K39/09;A61K39/102;A61K39/108;A61K39/39;A61P37/04;C07K14/00;C07K14/195;C07K14/41;C12P21/00;C12R1/19;C12R1/22;C12R1/43;(IPC1-7):A61K39/00;A61K39/10;C07G7/00 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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