摘要 |
<p>The invention releates to new peptide derivatives which act on the central nervous system and correspond to the general formula (I), Glp - X - Y - NH - A (I) wherein X is L-norleucyl, L-leucyl, L-norvalyl, D-leucyl, L-prolyl, L-2-aminobubyryl, L-valyl, L-threonyl, L-isoleucyl, L-2-amino-decanoyl, L-cyclohexylalanyl or L-terb.-butyl-seryl group and Y is L-prolyl group, or X is L-histidyl group and Y is L-homoprolyl or D-pipecolyl goup, furthermore A is hydrogen, a C1-10 alkyl group or a C1-3 alkyl group having a dime bdimethylamino substituent, with the proviso that if X is L-leucyl group, A is other than hydrogen, and pharmaceubically acceptable complexes thereof. These compounds are prepared by methods commonly applied in the peptide chemistry.</p> |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR RT. |
发明人 |
KISFALUDY, LAJOS;SZIRTES, TAMAS;BALASPIRI, LAJOS;PALOSI, EVA;SZPORNY, LASZLO;SARKADI, ADAM |