发明名称 UN PROCEDINIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE ACIDO ACETAMIDO PENICILANICO.
摘要 <p>A compound of formula (I) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof: <IMAGE> (I) wherein R1 is phenyl, 4-hydroxy phenyl, 3,4-dihydroxyphenyl, 3,4-diacetoxyphenyl or a 5- or 6- membered heterocyclic ring containing up to three heteroatoms selected from oxygen, sulphur or nitrogen, optionally substituted with hydroxy, amino, halogen or C1-6 alkoxy; and R2 is a sub-group of formula (A): -NH-R3 (A) wherein R3 is an optionally substituted C1-10 alkyl or C3-7 cycloalkyl group; or R2 is a sub-group of formula (B): -NH-CO-R4 (B) wherein R4 is an aryl group, an optionally substituted C1-10 alkyl group or a C1-6 alkyloxy group optionally substituted by an aryl group.</p>
申请公布号 ES513128(D0) 申请公布日期 1983.08.01
申请号 ES19280005131 申请日期 1982.06.15
申请人 BEECHAM GROUP PLC 发明人
分类号 C07D499/87;A61K31/43;A61P31/04;C07D239/46;C07D499/00;C07D499/64;C07D499/68;C07D499/70;C07D499/86;C07D499/897;(IPC1-7):07D499/44;61K31/43 主分类号 C07D499/87
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