| 发明名称 |
PROCEDIMENTO PER LA PREPARAZIONE DI UN ACIDO AMMINOLATTONCARBOSSILICO. |
| 摘要 |
<p>The invention relates to a process for the preparation of the compound of the formula I, <IMAGE> I which comprises (a1) splitting off the ethylene ketal protecting group from the azetidinone derivative of the formula IVa, <IMAGE> IVa reducing the compound of the formula III thus obtained, <IMAGE> III treating the resulting compound of the formula II <IMAGE> II with concentrated aqueous hydrogen chloride solution; or (a2) reducing the compound of the formula III, treating the compound of the formula II thus obtained with concentrated aqueous hydrogen chloride solution; or (a3) treating the compound of the formula II with concentrated aqueous hydrogen chloride solution; and isolating the compound of the formula I thus obtained from the reaction mixture. The compound of the formula I is useful as an intermediate in the production of thienamycin, a highly potent antibiotic.</p> |
| 申请公布号 |
IT8322323(D0) |
申请公布日期 |
1983.07.29 |
| 申请号 |
IT19830022323 |
申请日期 |
1983.07.29 |
| 申请人 |
RICHTER GEDEON VEGYESZETI CYAR R.T.;BIOGAL GYOGYSZERGYAR |
发明人 |
KAROLY LEMPERT;GABOR DOLESCHALL;JOZSEF FETTER;GYULA HORNYAK;JOZSEF NYITRAI;GYULA SIMIG;KAROLY ZAUER |
| 分类号 |
C07D205/08;C07D207/26;C07D207/277;C07D207/28;C07D309/30;C07D405/04;(IPC1-7):C07D/ |
主分类号 |
C07D205/08 |
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