摘要 |
Compounds represented by the general formula
<CHEM>
in which R<1> represents -CH3, -CH2CH3 or -(CH2)2 CH3;
R<2> represents -CONHR<4>, -F, -Cl, -Br, -I,
-CF3, -NO2, -NH2, -CH3, -OCH3
or -NHCOCH3, and
R<3> represents -CONHR<4>, -H, -CH3 or -OCH3, with the proviso that at least one of R<2> and R<3> represents -CONHR<4>;
and R<4> represents H, or -CH3, -CH2CH3, -(CH2)2CH3, -(CH2)3CH3 or - CH2CH(CH3)2, each optionally substituted with hydroxyl, amine and/or amide functions;
and acid addition salts thereof have antitumour properties. |