发明名称 SUBSTITUTED IMIDAZOLYLPHENYL AMIDINES,PROCESSES FOR THEIR PREPARATION,AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE
摘要 This invention relates to imidazolylphenyl amidines, the preparation thereof, and pharmaceutical compositions containing them. More particularly, this invention relates to compounds of the general formula <IMAGE> in which R, R1, R3, which may be the same or different, each represent a hydrogen atom or a lower alkyl group, and R2 represents a linear or branched alkyl, alkenyl, or alkynyl group, a cyano group, a hydroxyl group, a substituted or unsubstituted cycloalkyl or cycloaliphatic alkyl group, a bicyclic group, an aralkyl or aryl group optionally substituted by halogen, methyl, methoxy, or methylenedioxy groups, or a substituted or unsubstituted heterocyclylalkyl or heterocyclic group which may also contain a further hetero atom, or a non-toxic, pharmacologically acceptable acid addition salt thereof. These compounds are useful in treating disorders of the gastrointestinal tract.
申请公布号 ZA8108240(B) 申请公布日期 1983.07.27
申请号 ZA19810008240 申请日期 1981.11.27
申请人 ANGELI INST SPA 发明人 CEREDA ENZO;DONETTI ARTURO;SOLDATO PIERO DEL;BERGAMASCHI MARIO
分类号 C07D233/00;A61K31/415;A61K31/4164;A61K31/42;A61P1/04;C07C67/00;C07C241/00;C07C257/04;C07D233/54;C07D233/64;C07D405/12;C07D411/12;C07D413/12 主分类号 C07D233/00
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