发明名称 |
7 alpha -Methoxycephalosporins |
摘要 |
A 7 alpha -methoxycephalosporin represented by the general formula: <IMAGE> wherein R1 represents a hydrogen atom or a carboxyl-protecting group; R2 represents an organic group linked to the carbon atom through an oxygen or sulfur atom; R3 represents a lower alkyl group; n is 0, 1 or 2; A represents a hydrogen atom or a substituted or unsubstituted alkyl group; and B represents a substituted or unsubstituted alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl or heterocyclic group, and a salt thereof. These compounds have a broad antibacterial spectrum, high resistance to beta -lactamase produced from bacteria, and an effective antibacterial activity against clinical isolates of bacteria.
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申请公布号 |
US4395412(A) |
申请公布日期 |
1983.07.26 |
申请号 |
US19800221622 |
申请日期 |
1980.12.31 |
申请人 |
TOYAMA CHEMICAL CO., LTD. |
发明人 |
SAIKAWA, ISAMU;TAKANO, SHUNTARO;IMAIZUMI, HIROYUKI;TAKAKURA, ISAMU;OCHIAI, HIROKAZU;YASUDA, TAKASHI;TAKI, HIDEO;TAI, MASARU;KODAMA, YUTAKA |
分类号 |
C07D295/20;C07D501/24;C07D501/34;C07D501/36;C07D501/57;(IPC1-7):C07D501/57;A61K31/54 |
主分类号 |
C07D295/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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