摘要 |
A polypeptide antitumor antibiotic designated herein as BBM- 1644 is produced by fermentation of Actinomadura sp. strain H710-49 (ATCC 39144). BBM-1644 inhibits gram-positive and acid-fast bacteria, induces prophage in lysogenic bacteria and inhibits the growth of tumors such as P388 leukemia in mice. |