| 发明名称 |
POLYPRENYL CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
<p>A polyprenyl carboxylic acid derivative having the general formula (I): …<CHEM>… in which n is an integer of from 2 to 4, R1 represents the hydrogen atom or a protecting group for the carboxylic acid group, and R2 represents a hydroxymethyl, formyl or carboxyl group. A process for the preparation of the polyprenyl carboxylic acid derivative involving microbiological oxidation using a strain belonging to the genus Nocardia is disclosed. The polyprenyl carboxylic acid derivative also exhibits pharmacological activity and is useful in form of a pharmaceutical composition.</p> |
| 申请公布号 |
EP0040407(B1) |
申请公布日期 |
1983.07.13 |
| 申请号 |
EP19810103717 |
申请日期 |
1981.05.14 |
| 申请人 |
EISAI CO., LTD.;ISHIZAKA, SEIICHI PRESIDENT OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY |
发明人 |
SATO, AKIO;NAKAJIMA, KENJI;TAKAHARA, YOSHIMASA;KIJIMA, SHIZUMASA;INAI, YUICHI;KOHARA, YOSHIYUKI;KAWAKAMI, YOSHIYUKI;TSURUGI, TOMIO |
| 分类号 |
A61K31/19;A61K31/22;A61P1/04;A61P9/12;C07C51/00;C07C57/13;C07C59/42;C07C59/74;C07C67/00;C07C69/602;C07C69/73;C07C69/732;C12P7/40;C12P7/42;C12P7/44;C12P7/62;C12P7/64;(IPC1-7):07C59/42;07C69/732;07C69/73;07C69/602;12P7/42;12P7/44;12P7/64;61K31/20;07C59/13;12P7/62;07C59/74 |
主分类号 |
A61K31/19 |
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