| 摘要 |
<p>Described are compounds of the formula wherein R1 is wherein R5 and R6 are hydrogen, loweralkyl or together are alkylene of 4 or 5 carbon atoms, R2 is hydrogen, halo, haloloweralkyl, loweralkyl, loweralkoxy, loweralkylthio or wherein R5 and R6 are as previously defined, R3 is hydroxy, alkoxy, branched alkoxy, adamantyloxy, morpholino, amino or amino substituted by loweralkyl or alkylene of 4 or 5 carbon atoms, R4 is hydrogen or loweralkyl, and X1 and X2 are hydrogen, loweralkyl, halo or when substituted on adjacent carbon atoms of the benzene ring form a 1,3-butadienylene linkage, with the proviso that X1 and X2 are not both hydrogen, and pharmaceutically acceptable salts thereof, the compounds are effective as diuretic agents in increasing urinary excretion.</p> |
