发明名称 |
4-(Substituted alkyl)-N-(1,3-dithiolan-2-ylidene(aniline |
摘要 |
N-(1,3-dithiolan-2-ylidene)-4-alkylanilines having a hydroxy, alkoxy or alkanoyloxy substituent on the alkyl group are useful as anti-inflammatory agents, as analgesic agents and as antiasthmatic agents. The compounds involved can be prepared by the reaction of an appropriate 4-alkylaniline with a methyl(1,3-dithiolan-2-ylidene)sulfonium salt or with carbon disulfide and ethylene dibromide in the presence of a base.
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申请公布号 |
US4391818(A) |
申请公布日期 |
1983.07.05 |
申请号 |
US19820367540 |
申请日期 |
1982.04.12 |
申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
HARRISON, BOYD L.;DOHERTY, NIALL S. |
分类号 |
A61K31/385;A61P11/00;A61P25/04;A61P29/00;C07C205/19;C07C205/34;C07C205/56;C07D339/06;(IPC1-7):A61K31/38 |
主分类号 |
A61K31/385 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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