POLYMER FOER OEVERDRAG AV FODERMEDEL NAERINGSMEDEL OCH FARMACEUTISKA BEREDNINGAR MED PH-BEROENDE LOESLIGHETSEGENSKAPER I VATTENHALTIGA MEDIER FOERFARANDE FOER DESS FRAMSTAELLNING OCHPRODUKT I PARTIKELFORM OEVERDRAGEN MED POLYMEREN SAMT FOE RFRANDE FOER TILLFOERSEL AV PRODUKTER OEVERDRAGNA MED POLYM ERN TILL IDISSLANDE DJUR

摘要

The present invention relates to polymers which have pH-depending solubility characteristics in aqueous solutions, whereby the polymers are copolymers between (a) methylmethacrylate (b) at least a monomer of the formula III wherein R3 is an alkyl group having 4 to 18 carbon atoms and R4 is hydrogen or methyl; and (c) a monomer of the formula I wherein R is hydrogen or methyl, n is an integer of from 1 to 4, and X is =CH2 or =O; and/or a monomer of the formula II wherein R is hydrogen or methyl, R1 and R2 are each hydrogen, methyl, ethyl, propyl, isopropyl, isobutyl, t-butyl or n-butyl, and m is an integer of from 1 to 4, as well as a process for their preparation, and a product in the form of particles which have been coated with such a polymer, whereby the product is protected against dissolution at pH above 5, but shall be dissolved at pH below 4, the product preferably being one which is administered to ruminants in order to obtain rumen-by-pass.