HUMAN MONOCLONAL ANTIBODIES OR LYMPHOKINES IN SEPARATION OF CELLS OR DIAGNOSIS OF MAMMARY CANCER

摘要

Method for separating fused cells, resulting from fusion of human cells known to produce a specific antibody or a specific lymphokine with malignant human partner cells, from the said partner cells which comprises addition of specific antiserum capable of identifying antigenic specificities unique to the clone and non-reactive with the non-fused partner cells. After reaction of the fused cell with the antiserum, the reaction product is separated within 24 hours by indirect rosetting. The monoclonal antibodies may be employed in in vitro testing for malignancies.