发明名称 PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE ETENILIMIDAZOL.
摘要 <p>The invention relates to new ethenylimidazoles of the formula <CHEM> in which n is 0, 1 or 2, R1 represents a halogen atom, a trifluoromethyl group or an alkyl or alkoxy group with at most 6 carbon atoms, the two substituents being the same or different when n is 2, R2 represents an alkyl group with 1 to 6 carbon atoms, an alkenyl group with 2 to 4 carbon atoms or a cycloalkyl group with 3 to 6 carbon atoms, R3 represents a hydrogen atom, an alkyl group with 1 to 6 carbon atoms or an alkenyl group with 2 to 4 carbon atoms and R4 represents a hydrogen atom, an alkyl group with 1 to 6 carbon atoms or a nitro group, and their acid addition salts. Other features of the invention are - processes for the preparation of compounds of formula I, - pharmaceutical compositions comprising a compound of formula I, - novel phosphine oxides of the formula <CHEM> in which R5 and R6 are the same or different and each represents an unsubstituted or substituted phenyl group and R3 and R4 are as defined above, - a process for the preparation of phosphine oxides of formula XI.</p>
申请公布号 ES516552(D0) 申请公布日期 1983.06.16
申请号 ES19520005165 申请日期 1982.10.15
申请人 GIST-BROCADES N.V. 发明人
分类号 A61K31/415;A61P31/04;C07D233/56;C07D233/58;C07D233/60;C07D233/92;C07D233/93;C07D233/94;C07D521/00;C07F9/6506;(IPC1-7):07D233/54 主分类号 A61K31/415
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