| 摘要 |
NEW MATERIAL:Antibiotics DC-45-A1 and A2 shown by the formulaI(R is a grop shown by the formula II or H). DC-45-A1 Substance. Melting point: 184- 186 deg.C. Value of elemental analysis (%): H 5.96, C 57.77, Molecular weight: 704. Molecular formula: C34H44O16. Specific rotatory power:[alpha]<25>D+103 deg. (C=0.5, CHCl3). Solubility: soluble in methanol, acetone, etc., slightly soluble in benzene, ether, and water, insoluble in n-hexane. DC-45-A2 Substance. Melting point: 152- 158 deg.C. Value of elemental analysis (%): H 5.23, C 57.80. Molecular weight: 518. Molecular formula: C25H26O12. Specific rotatory power:[alpha]<25>D+97.5 deg. (C=0.5, CHCl3). Solubility: as shown for A1. USE:An antitumor agent. PROCESS:Bacterium belonging to the genus Streptomyces is cultivated in a medium to give a compound shown by the formulaI(DC-45-A1 when R is a group shown by the formula II and DC-45-A2 when R is H), or it is synthesized from DC-A. |
