| 摘要 |
<p>For the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A novel benzhydrylsulfinylacetamide derivative characterized in that it is selected from the group consisting of compounds of the general formula : see diagramm : EP0097071,P21,F1 wherein - X1 and X2 , which may be identical or different each represent H, Cl or F, - Z1 represents CH3 , CH2 CH3 , CH(CH3 )2 or C(CH3 )3 , Z1 may represent the hydrogen atom when at least one of X1 and X2 is different from H, - Z2 represents H ; NZ1 Z2 considered together may represent a piperidino or morpholino group. For the contracting state AT 1. A method for the preparation of a novel benzhydrylsulfinylacetamide derivative of the general formula : see diagramm : EP0097071,P22,F1 wherein : - X1 and X2 which may be identical or different each represent H, Cl or F, - Z1 represents CH3 , CH2 CH3 , CH(CH3 )2 or C(CH3 )3 , Z1 may represent the hydrogen atom when at least one of X1 and X2 is different from H, - Z2 represents H ; NZ1 Z2 considered together may represent a piperidino or morpholino group, characterized in that an acid chloride of general formula see diagramm : EP0097071,P22,F2 wherein X1 and X2 are as defined above, is reacted with an amine of general formula HNZ1 Z2 wherein Z1 and Z2 have the above definition, to a benzhydrythiocetamide derivative of general formula see diagramm : EP0097071,P22,F3 wherein X1 , X2 , Z1 and Z2 are as defined above, and the obtained benzhydrylthiocetamide derivative of formula (IV) is oxidized.</p> |
