发明名称 Salicylic derivatives of N-acetylcysteine.
摘要 <p>The thioester of pharmaceutically N-acetylcysteine with salicylic acid and the pharmacologically acceptable and non toxic organic and inorganic salts thereof, show some interesting therapeutic properties both as anti-pyretic, anti-inflammatory and analgesic activities and as mucolytic activity.</p><p>The method for the preparation of the compounds of the invention provided the reaction of the chloride of acetylsalicylic acid or of the mixed anhydride of the acetylsalicylic acid, in an aqueous medium and at low temperature, with N-acetylcysteine.</p>
申请公布号 EP0080229(A1) 申请公布日期 1983.06.01
申请号 EP19820201443 申请日期 1982.11.12
申请人 PIETRO ISNARDI & C. SPA 发明人 PONCHIROLI, OSVALDO
分类号 A61P29/00;C07C323/59;A61K31/60;A61P11/10;A61P25/04;C07C67/00;C07C227/00;C07C227/18;C07C325/00;C07C327/34;C07H17/04;C07H17/08;(IPC1-7):07C153/11;61K31/615;61K31/71;61K31/195;07H17/08;61K31/65;07C103/19;07C101/24 主分类号 A61P29/00
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