发明名称 |
Pyrimidone derivatives |
摘要 |
This invention relates to 2-amino-4-pyrimidone derivatives, in which the amino group is substituted by a methylthioethyl, butyl or oxypropyl group bearing a terminal 4-dialkylaminomethyl-2-pyridyl group. The compounds have histamine H2-antagonist activity. A specific compound of this invention is 2-[2-(4-dimethylaminomethyl-2-pyridylmethylthio)ethylamino]-5-(6-methy l-3-pyridylmethyl)-4-pyrimidone.
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申请公布号 |
US4385058(A) |
申请公布日期 |
1983.05.24 |
申请号 |
US19810302941 |
申请日期 |
1981.09.16 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES LIMITED |
发明人 |
COOPER, DAVID G.;SACH, GEORGE S. |
分类号 |
C07D401/12;A61K31/505;A61P43/00;C07D213/38;C07D401/14;C07D405/14;C07D409/14;C07D417/14;(IPC1-7):C07D401/12 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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