Esters of ortho-allylphenol useful for the preparation of arylacetic acid derivatives

摘要

New compounds of the formula (VIIIa) are disclosed <IMAGE> wherein R1 is hydrogen, methyl or ethyl; R2 is hydrogen, fluoro, or alkyl having 1 to 4 carbon atoms; R3 is hydrogen, phenyl, alkoxy having 1 to 6 carbon atoms; phenoxy, thenoyl, or benzoyl; or R2 and R3 together with the phenyl group to which they are attached form a naphthyl group which is unsubstituted or substituted by C1 to C4 alkyl or C1 to C4 alkoxy; R10 is phenylaminocarbonyl, 1-phenyl-5-tetrazolyl, a group -SO2OMe, wherein Me is a metal atom selected from the group which consists of sodium or potassium, or a group -SO2R6 in which R6 is alkyl having 1 to 4 carbon atoms, 4-methylphenyl, amino, C1 to C4 alkoxycarbonyl-amino, or benzoylamino, or R10 is a group <IMAGE> in which R7 is cycloalkyl having 5 to 6 carbon atoms, and R is vinyl. The compounds are intermediates useful in the preparation of arylacetic acids having antiinflammatory compounds.