发明名称 |
7-OXO-1-AZABICYCLO 3.2.0 HEPT-2-ENE DERIVATIVES |
摘要 |
The compound of formula (II): <CHEM> namely (5R, 6S)-3-[2-(Z)-(2-aminoethoxycarbonyl)ethenylthio]-6-[(R)-1-hydroxyethyl ]-7-oxo-1- azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid; is useful in the treatment of a bacterial infection in animals and is preferably administered as a pharmaceutical formulation in association with a pharmaceutically acceptable carrier. Tne compound may be prepared by, e.g. reaction of the thiol with a compound of formula (V): H-C IDENTICAL C-CO2CH2CH2X (V) wherein X is amino or a precursor thereof. |
申请公布号 |
AU9023682(A) |
申请公布日期 |
1983.05.19 |
申请号 |
AU19820090236 |
申请日期 |
1982.11.08 |
申请人 |
BEECHAM GROUP P.L.C. |
发明人 |
STEVEN COULTON;DAVID FRANCIS CORBETT |
分类号 |
C07D477/00;A61K31/397;A61K31/40;A61P31/04;C07D477/20 |
主分类号 |
C07D477/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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