摘要 |
Calcium saccharin (C7H4NO3S)2 Ca is produced by addition of calcium carbonate to an agitated aqueous suspension of free saccharin at 50- 55 DEG C until a pH of 4.5 to 5.75 is reached, filtering, and crystallising the filtrate. It retains the sweetness of sodium saccharin and is pharmacologically more acceptable. |