| 摘要 |
<p>There are provided peptides of the formula X-A-Pro-Pro-Ile-Ser-B-C-Leu-D-E-F-G-W wherein X is H, a terminal N atom protecting group, or a residue of a natural L-amino acid, optionally protected by a terminal N atom protecting group; A is a L-amino acid residue or a glycine residue; B is a neutral L-amino acid residue; C is a neutral or acidic L-amino acid residue; D is a L-amino acid residue which contains in the side chain an alcoholic hydroxy group, optionally protected by a conventional hydroxy protecting group; E is a valence bond or a neutral L-amino acid residue; F is a valence bond or a L-amino acid residue; G is a valence bond or a neutral L-amino acid residue; W is OH, NH2, OR, NHR, NR2 or NH-NH-R'; wherein R and R' are optionally substituted hydrocarbon. Pharmaceutically acceptable salts of these peptides are also provided.</p> |
