| 摘要 |
(2R,6R)-1-Chloro-2,6,10-trimethyl-undecane I, (R)-(+)- beta -chloro-isobutyric acid II, (S)-(+)-1-bromo-3-chloro-2-methylpropane IV and (2R)-(+)-1-chloro-2,6-dimethyl-heptane V are novel optically active units for the synthesis of the side chain of (R,R,R)- alpha -tocopherol. In the process according to the invention, the optically active C14-chloride I is obtained in 6 simple reaction steps starting from II, via the novel intermediates IV and V, in accordance with the following equation: <IMAGE> (II) <IMAGE> (III) <IMAGE> (IV) <IMAGE> (V) <IMAGE> (VI) <IMAGE> &bhbrace& (VII) + (IV) <IMAGE> (I) |
