Opiate agonists and antagonists.

摘要

DDihydromorphinone compound of the general formula
in which R1 is an optionally substituted alkyl, alkylene, cycloalkyl, or cycloalkylene
R2 is OH or HR3 is OH or OCH3 andR is N=R4, N-R4,
R4 is an optionally substituted alkyl, alkylene, cycloalkyl, cycloalkylene, aryl, heterocycloalkyl, heterocycloalkylene, or alkenyl, andn is 1-10, and use thereof as an opiate receptor blocker.