| 发明名称 |
1.4-Naphthoquinones, methods for their preparation, pharmaceutical and veterinary formulations thereof. |
| 摘要 |
<p>1,4-Naphthoquinones of formula (I), methods for their preparation, pharmaceutical and veterinary formulations thereof and the use thereof in human and animal therapy are disclosed.</p><p><Chemistry id="chema01" num="0001"><Image id="ia01" he="28" wi="79" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>Particularly preferred compounds of formula (I) are 2-(4'-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone and 2-hydroxy-3-(4'-t-pentylcyclohexyl)-1,4-naphthoquinone. The compounds are of value as antiprotozoal agents, in particular antimalarial and anticoccidial agents.</p> |
| 申请公布号 |
EP0077551(A2) |
申请公布日期 |
1983.04.27 |
| 申请号 |
EP19820109569 |
申请日期 |
1982.10.15 |
| 申请人 |
THE WELLCOME FOUNDATION LIMITED |
发明人 |
HUDSON, ALAN THOMAS;RANDALL, ANTHONY WINCHESTER |
| 分类号 |
A61K31/05;A61K31/12;A61K31/122;A61P17/00;A61P27/02;A61P29/00;A61P33/02;A61P43/00;C07C45/00;C07C46/00;C07C50/24;C07C50/32;C07C51/08;C07C51/353;C07C51/36;C07C51/487;C07C53/134;C07C61/08;C07C61/15;C07C61/22;C07C67/00;(IPC1-7):07C50/32;61K31/12;07C69/14;07C46/00;07C69/78 |
主分类号 |
A61K31/05 |
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