| 发明名称 |
4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones |
| 摘要 |
1,3-Dihydro-2H-imidazol-2-ones having 5-acyl and 4-(substituted amino)methyl substituents, are useful as cardiotonics, antihypertensives and antithrombotic agents. The compounds are obtained by the reaction of an appropriate amine with a substituted 4-bromomethyl-1,3-dihydro-2H-imidazol-2-one.
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| 申请公布号 |
US4381393(A) |
申请公布日期 |
1983.04.26 |
| 申请号 |
US19810260446 |
申请日期 |
1981.05.04 |
| 申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
GRISAR, J. MARTIN;SCHNETTLER, RICHARD A.;DAGE, RICHARD C. |
| 分类号 |
A61K31/415;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/495;A61K31/535;A61P7/02;A61P9/12;C07D233/70;C07D233/90;C07D401/06;C07D405/06;C07D409/06;(IPC1-7):C07D403/00;C07D401/00;C07D233/30 |
主分类号 |
A61K31/415 |
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