| 摘要 |
Novel derivatives of known bio-affecting carboxylic acids R-COOH are disclosed, said derivatives having the structural formula <IMAGE> (I) wherein Y and Y' are each H or C1-C4 alkyl; n is 0 or 1; R1 and R2 are each selected from a variety of unsubstituted or substituted hydrocarbon radicals, or are combined so that -NR1R2 represents the residue of a saturated or unsaturated heterocyclic compound containing one secondary nitrogen atom; and R3 is H or one of a variety of other substituents. Salts and N-oxides of compounds of formula (I) and the corresponding diacyloxy derivatives of known bio-affecting carboxylic acids HOOC-R'-COOH are disclosed also. The parent acids from which the subject soft tertiary amine esters can be derived include such bio-affecting agents as cephalosporin and penicillin antibiotics, amino acids and structurally related compounds, prostaglandins and their metabolites, steroidal anti-inflammatory agents, and non-steroidal anti-inflammatory/non-narcotic analgesic/antipyretic agents.
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