发明名称 CRYSTALLINE FORMS OF N-2-(6-METHOXY) BENZOTHIAZOLYL N'-PHENYL UREA
摘要 <p>Described herein are (1) the crystalline monohydrate form (form III) and the crystalline anhydrate form (form IV) of the compound N-2-(6-methoxy) benzothiazolyl -N'-phenylurea, which (in the anhydrate form) has the chemical formula These crystalline forms of said compound, (which has the generic name of frentizole) are stable, have a greater bulk density, are less electrostatic, and are more freely flowing than previous crystalline forms of this compound, and are substantially free of mutagenic impurities.</p>
申请公布号 CA1144932(A) 申请公布日期 1983.04.19
申请号 CA19820401603 申请日期 1982.04.23
申请人 LILLY (ELI) AND COMPANY 发明人 LAPPAS, LEWIS C.;LORENZ, LESLIE J.;WIKEL, JAMES H.
分类号 C07D277/80;A61K31/428;A61P31/06;A61P37/00;C07D277/82;(IPC1-7):C07D277/82 主分类号 C07D277/80
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