发明名称 |
ANTICORPI AVENTI DOPPIE SPECIFICITA', LORO PREPARAZIONE ELORO IMPIEGHI. |
摘要 |
Described herein are "polydomas", the product of the fusion of a hybridoma with a B-lymphocyte or another hybridoma. The polydomas produce a hybrid monoclonal antibody having a dual specificity against two different antigenic determinants. Also described are immunodiagnostic and immunotherapeutic processes which utilize the hybrid monoclonal antibodies or other antibodies having a dual specificity. In those processes, one specificity of the antibody is directed against a target antigen and the other against a moiety which permits a diagnosis to be made or which delivers an agent lethal to the target antigen or associated tissue. |
申请公布号 |
IT8320548(D0) |
申请公布日期 |
1983.04.12 |
申请号 |
IT19830020548 |
申请日期 |
1983.04.12 |
申请人 |
HYBRITECH INCORPORATED |
发明人 |
JOANNE MARTINIS;RICHARD M. BARTHOLOMEW;GARY S. DAVID;THOMAS H. ADAMS;JAMES M. FRINCKE |
分类号 |
A61K39/395;A61K;A61K45/00;A61K51/00;A61K51/10;C07G;C07K16/00;C07K16/46;C07K19/00;C12N;C12N5/00;C12N5/10;C12N5/12;C12N5/20;C12N15/00;C12N15/02;C12P21/00;C12P21/08;C12R1/91;G01N;G01N33/53;G01N33/531;G01N33/536;G01N33/542;G01N33/543;G01N33/573;G01N33/576;G01N33/577 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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