| 摘要 |
PURPOSE:To provide a carcinostatic agent containing cancer cell-disturbing lymphocyte (killer T-cell) specific to cancer cell-originated saccharide chain- relating antigen (GRA) as an active component. CONSTITUTION:The cell membrane component is removed from the GRA of the cultured cancer cell, transplanted cancer cell, spontaneously occured cancer cell, chemically or virally induced cancer cell, cancer cell originated from the operation tissue, etc. of man or animals, and the GRA is treated with lectin (e.g. peanut lectin, castor bean lectin, etc.) which bonds specifically to the terminal galactose. Lymphocytes are sensitized with said GRA to obtain killer T cells. The objective carcinostatic agent active specifically to cancer cells can be obtained by using said killer T-cell as an active component. The agent is preferably administered in the form of injection together with a carrier such as physiological saline water, etc. The concentration of the killer T-cell is preferably 10<5>-10<12>/ml, and the daily dose is 10<5>-10<12>/kg in 1-several doses. |
