摘要 |
NEW MATERIAL:A compound expressed by formulaI[R<1> is ribose residue, arabinose residue, xylose residue, 2-deoxyribose residue or 3-deoxyribose residue which may have a protecting group; X is -SR<2> (R<2> is lower alkyl), -OR<2> or -NR<3>R<4> (R<3> is lower alkyl, hydroxyl or amino; R<4> is H or lower alkyl)]. EXAMPLE:2-Dimethylamino-6-methyl-9-beta-D-ribofuranosylpurine. USE:A reagent for biochemical research and a sun-screening ultraviolet light absorber having the adenyl deaminase inhibitory, antitumor activity, etc. PROCESS:A 2-fluoro-6-methylpurine nucleoside expressed by formula II is reacted with a nucleophilic reagent expressed by the formula R<2>S<->, R<2>O<-> or NHR<3>R<4> to give the compound expressed by formulaI. |