摘要 |
Compounds of the formula <IMAGE> wherein R2 is hydrogen, chlorine, bromine, formyl, acetyl, alkyl of 1 to 4 carbon atoms, nitro, cyano or -CH2-A; where A is (alkyl of 1 to 2 carbon atoms)-amino; di(alkyl of 1 to 2 carbon atoms)-amino, where one of the alkyl moieties may have a terminal hydroxyl substituent attached thereto; or a 5-, 6- or 7-membered saturated, nitrogen-containing heterocycle which is attached to the methylene group through the nitrogen atom and may have a hydroxyl or hydroxymethyl substituent attached to a ring carbon atom, and the 6-membered heterocycle may contain oxygen as an additional ring heteroatom in the p-position; R3 is hydrogen, fluorine, chlorine, bromine, methyl or methoxy; and R4 is hydrogen or alkyl of 1 to 3 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants. |