发明名称 NOVEL 4-PHENYL-4,5,6,7-TETRAHYDRO-PYRROLO(2,3-C)PYRIDINES AND SALTS THEREOF
摘要 Compounds of the formula <IMAGE> wherein R2 is hydrogen, chlorine, bromine, formyl, acetyl, alkyl of 1 to 4 carbon atoms, nitro, cyano or -CH2-A; where A is (alkyl of 1 to 2 carbon atoms)-amino; di(alkyl of 1 to 2 carbon atoms)-amino, where one of the alkyl moieties may have a terminal hydroxyl substituent attached thereto; or a 5-, 6- or 7-membered saturated, nitrogen-containing heterocycle which is attached to the methylene group through the nitrogen atom and may have a hydroxyl or hydroxymethyl substituent attached to a ring carbon atom, and the 6-membered heterocycle may contain oxygen as an additional ring heteroatom in the p-position; R3 is hydrogen, fluorine, chlorine, bromine, methyl or methoxy; and R4 is hydrogen or alkyl of 1 to 3 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.
申请公布号 PH15756(A) 申请公布日期 1983.03.18
申请号 PH19460000242 申请日期 1980.07.07
申请人 BOEHRINGER SOHN INGELHEIM 发明人 SCHNEIDER CLAUS;BOEKE KARIN;WEBER KARL HEINZ;WALTHER GERHARD;BECHTEL WOLF DIETRICH
分类号 A61K31/435;A61K31/445;A61K31/535;A61P25/02;A61P25/24;A61P25/26;A61P43/00;C07D207/32;C07D207/335;C07D471/04 主分类号 A61K31/435
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