| 发明名称 |
METHOD FOR PENTAHYDRATE OF CEPHALOSPORINE DERIVATIVE OBTAINING |
| 摘要 |
<p>(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)ace tamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate in the form of its crystalline pentahydrate. This pentahydrate has a well defined crystalline structure and exhibits good stability on storage. The pentahydrate exhibits excellent antibiotic activity, particularly against organisms which are normally difficult to combat with beta -lactam antibiotics.</p> |
| 申请公布号 |
BG33586(A3) |
申请公布日期 |
1983.03.15 |
| 申请号 |
BG19800049206 |
申请日期 |
1980.10.01 |
| 申请人 |
GLAXO GROUP LTD |
发明人 |
BRODIE,ALASTAIR C.;WETHERILL,LEWIS A. |
| 分类号 |
C07D501/00;A61K;A61K31/54;A61K31/545;A61K31/546;A61P31/04;C07D;C07D417/12;C07D501/12;C07D501/46;C07D501/56;C07D501/60;(IPC1-7):C07D501/46 |
主分类号 |
C07D501/00 |
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