摘要 |
PURPOSE:The titled remedy, containing a cyclohexanecarboxylic acid derivative as an active constituent, and having the anticomplementary action, inhibitory action on blood platelet agglutination, anti-inflammatory action, inhibitory action on cellular immunity, etc. with low toxicity. CONSTITUTION:A preventing agent and remedy for renal diseases, containing a cyclohexanecarboxylic acid derivative of formulaI(A is 1-4C lower alkyl, 1- 4C lower alkoxyl, halogen, nitro, hydroxyl group, carboxyl, phenyl or pyridyl; R is alkyl; R<1> is H or methyl) as an active constituent. An oral agent, e.g. a tablet or capsule, a parenteral agent, e.g. an injection or suppository, may be cited as the dosage form, and the amount of the active constituent in the unit dosage form is preferably 25-2,000mg. The active constituent of formulaIis prepared by reacting a reactive derivative of a cyclohexanecarboxylic acid derivative of formula II with a compound of formula III. |