发明名称 PREVENTING AGENT AND REMEDY FOR RENAL DISEASE
摘要 PURPOSE:The titled remedy, containing a cyclohexanecarboxylic acid derivative as an active constituent, and having the anticomplementary action, inhibitory action on blood platelet agglutination, anti-inflammatory action, inhibitory action on cellular immunity, etc. with low toxicity. CONSTITUTION:A preventing agent and remedy for renal diseases, containing a cyclohexanecarboxylic acid derivative of formulaI(A is 1-4C lower alkyl, 1- 4C lower alkoxyl, halogen, nitro, hydroxyl group, carboxyl, phenyl or pyridyl; R is alkyl; R<1> is H or methyl) as an active constituent. An oral agent, e.g. a tablet or capsule, a parenteral agent, e.g. an injection or suppository, may be cited as the dosage form, and the amount of the active constituent in the unit dosage form is preferably 25-2,000mg. The active constituent of formulaIis prepared by reacting a reactive derivative of a cyclohexanecarboxylic acid derivative of formula II with a compound of formula III.
申请公布号 JPS5843918(A) 申请公布日期 1983.03.14
申请号 JP19810122790 申请日期 1981.08.04
申请人 HISAMITSU SEIYAKU KK 发明人 NODA KANJI;NAKAGAWA AKIRA;MOTOMURA TOSHIHARU;SHIMOZONO YUUJI;IDE HIROYUKI
分类号 A61K31/16;A61K31/165;A61K31/195;A61K31/24;A61K31/44;A61P7/02;A61P13/02;A61P15/00;A61P29/00;A61P37/06;C07D213/75;C07D213/78 主分类号 A61K31/16
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