发明名称 METHOD OF MANUFACTURE OF NOVEL DERIVATIVES OF TETRAHYDROQUINOLINE
摘要 <p>A 1-acyl-8-[2,3-epoxypropoxy]- and/or 1-acyl-8-[3-halo-2-hydroxypropoxy]-1,2,3,4-tetrahydroquinoline are reacted with primary and secondary amines to obtain corresponding physiologically-active 1-acyl-8-[3-amino-2-hydroxypropoxy]-1,2,3,4-tetrahydroquinolines and pharmacologically-acceptable acid-addition salts thereof. These compounds are useful as such or in conventional medicament compositions for treating those afflicted with heart ailments and/or hypertension.</p>
申请公布号 PL124596(B1) 申请公布日期 1983.02.28
申请号 PL19800226434 申请日期 1980.08.27
申请人 发明人
分类号 A61K31/47;A61P9/06;C07D215/26;C07D401/06;C07D405/06;C07D409/04;(IPC1-7):07D215/26 主分类号 A61K31/47
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