发明名称 PROCESS FOR PRODUCING 6- AND 9-SUBSTITUTED 2-AMINO-PURINE DERIVATIVES
摘要 9-[2-(2-Hydroxyethoxy)ethoxymethyl] and related derivatives of certain 2-amino-6-substituted purines have been discovered to have potent anti-viral activities. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical formulations containing the compounds of this invention, and the treatment of viral infection with these formulations are all disclosed. 9-[2-(2-hydroxyethoxy)ethoxymethyl] guanine and 2-amino-9-[2-(2-hydroxyethoxy)ethoxymethyl] adenine, i.e. 2,6-diamino-9-[2-(2-hydroxyethoxy)ethoxymethyl] purine, are examples of especially active compounds of this invention.
申请公布号 HU180321(B) 申请公布日期 1983.02.28
申请号 HU1977WE00551 申请日期 1977.03.01
申请人 THE WELLCOME FOUNDATION LTD,GB 发明人 SCHAEFFER,HOWARD,J.,US
分类号 C07D473/16;A61K31/52;A61K31/522;A61P31/12;C07D473/00;C07D473/18;C07D473/30;C07D473/40;(IPC1-7):07D473/16;07D473/18;07D473/40 主分类号 C07D473/16
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