发明名称 |
PROCESS FOR PRODUCING PHARMACEUTICALLY ACTIVE 2-BRACKET-4-AMINO-BUTOXY-BRACKET CLOSED-STYLBENE DERIVATIVES |
摘要 |
<p>2-(4-Aminobutoxy) stilbenes having the formula (I): <CHEM> wherein R<1> is (1)- <CHEM> wherein R<2> and R<3> are each hydrogen or C1-C3 alkyl, (2) -N N-R<4> wherein R<4> is C1-C3 alkyl which may be substituted with hydroxy, or (3) hydroxypiperidino; and <CHEM> benzene rings, at least one of which contains one or more substituents selected from halogen, C1-C3 alkyl, C1-C3 alkoxy, <CHEM> wherein R<5> and R<6> are each C1-C3 alkyl, nitro and R<7>O@- wherein R@ is C1-C3 alkyl, and an acid addition salt thereof, are prepared and found useful as pharmaceutical agents, particularly as anti-convulsants and skeletal muscle relaxants. </p> |
申请公布号 |
HU180375(B) |
申请公布日期 |
1983.02.28 |
申请号 |
HU19800002022 |
申请日期 |
1980.08.14 |
申请人 |
MITSUBISHI CHEMICAL INDUSTRIES LTD,JP |
发明人 |
KIKUMOTO,RYOJI,JP;TOBE,AKIHIRO,JP;FUKAMI,HARUKAZU,JP;EGAWA,MITSUO,JP;NINOMIYA,KUNIHIRIO,JP |
分类号 |
A61K31/13;A61K31/135;A61K31/395;A61P25/08;C07C67/00;C07C213/00;C07C217/18;C07C217/80;C07D211/42;C07D295/08;C07D295/092;(IPC1-7):07C93/06;07D295/08;07D211/44 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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