| 摘要 |
Polymers containing 55 to 90% of units of the formula (A): <IMAGE> (A) wherein R1 is a hydrogen atom or an alkyl group of 1 to 3 carbon atoms; and 10 to 45% of units of the formula (B) and (C): <IMAGE> (B) <IMAGE> (C) wherein R2 is a hydrogen group of 5 to 19 carbon atoms, for example n-C11H23, R3 is a hydrogen atom or an alkyl group of 1 to 3 carbon atoms, R4 is a hydrocarbon group of 5 to 19 carbon atoms, for example n-C11H23 and X-is an anion and which contain at least 10% of units of formula (C) and are free from polymeric species having a molecular weight of less than 10,000 are described. The polymers possess antimicrobial activity agains common pathogens. Isotonic aqueous solutions containing 0.002 to 0.025% of the polymer are suitable for the sterilization of contact lenses for example by immersion of the lens in the solution overnight. Hydrophilic ointments containing from 0.002 to 0.25% of the polymer are suitable for the treatment of bacterial infection of lesions of the skin such as burns and ulcers. |
