发明名称 |
5-ASA Drug delivery system |
摘要 |
The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.
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申请公布号 |
US4374932(A) |
申请公布日期 |
1983.02.22 |
申请号 |
US19810271748 |
申请日期 |
1981.06.08 |
申请人 |
G. D. SEARLE & CO. |
发明人 |
PITZELE, BARNETT S.;JONES, PETER H. |
分类号 |
A61K31/785;A61K47/48;A61P1/04;C07C245/08;(IPC1-7):B01J41/14;A61K31/74 |
主分类号 |
A61K31/785 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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