发明名称 FOERFARANDE OCH MELLANPRODUKT FOER FRAMSTAELLNING AV FARMAKOLOGISKT VAERDEFULLA 1-FENYLINDAZOL-3-ON-FOERENINGAR
摘要 New 1-phenylindazol-3-one compounds are described which have the formula I <IMAGE> I where R1 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy or trifluoromethyl radical, R2 is a hydrogen or halogen atom, or a lower alkyl or lower alkoxy radical, R3 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy or trifluoromethyl radical, R4 is a hydrogen or halogen, atom, or a lower alkyl or lower alkoxy radical, Z is an alkylene radical with 2 to 6 carbon atoms and R5 is an unsubstituted or substituted pyridyl radical, a thienyl radical or an unsubstituted or substituted phenyl radical. The compounds have pharmacological actions, for example antiallergic actions. Methods of preparing these compounds are described as well as intermediates useful in these methods. Pharmaceutical compositions containing the compounds are also described.
申请公布号 FI822884(L) 申请公布日期 1983.02.21
申请号 FI19820002884 申请日期 1982.08.19
申请人 KALI-CHEMIE PHARMA GMBH 发明人 HEINEMANN, HENNING;JASSERAND, DANIEL;MILKOWSKI, WOLFGANG;YAVORDIOS, DIMITRI;ZEUGNER, HORST
分类号 A61K31/415;A61K31/495;A61P37/08;C07D231/56;C07D401/12;C07D405/12;C07D409/12 主分类号 A61K31/415
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