发明名称 PREPARATION OF DEHYDROPEPTIDES
摘要 <p>A preparation of azlactones represented by the formula II wherein R is a substituted or unsubstituted alkyl, aryl or nitrogen containing heterocyclic group, and R1 is an N-blocked amino acid residue or peptide chain, and stereoisomers thereof, by oxidizing tne corresponding saturated azlactone with a benzoquinone oxidizing agent in the presence of a base is disclosed. The unsaturated azlactones, some of which are novel, can be converted to dehydro peptides, which are useful as intermediates for preparing novel biologically active compounds, or themselves have biological activity.</p>
申请公布号 CA1141374(A) 申请公布日期 1983.02.15
申请号 CA19790330262 申请日期 1979.06.21
申请人 RESEARCH CORPORATION 发明人 STAMMER, CHARLES H.
分类号 C07D263/42;C07C67/00;C07C231/00;C07C231/10;C07K1/00;C07K1/02;C07K1/113;C07K5/062;C07K5/078;C07K5/083;C07K5/097;C07K5/103;C07K5/117;C07K7/04;(IPC1-7):07C103/52 主分类号 C07D263/42
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