发明名称 PRODUCTION OF HUMAN T-CELL GROWTH FACTOR (HTCGF)
摘要 PURPOSE:Human-originating cells, which are capable of producing hTCGF, are proliferated in a warm-blood animal to produce the hTCGF in high efficiency. CONSTITUTION:Human-originating cells, which are capable of producing hTCGF, such as human peripheral hemocytes, are transplanted in a body of blood-warm animal other than human as young as possible. Or a difusion chamber provided with a porous filtration membrane that prevents animal cells from passing through is embedded in an animal body to effect the proliferation of the human cells as they are receiving nutrients from the animal body for 1-20 weeks. Thus, the number of the proliferated human-originating cells reaches 10<2>-10<7> or more times that of the initially transplanted cells, which corresponds to 10<1>- 10<6> times that of the cells, when they are proliferated in vitro in an enriched culture medium.
申请公布号 JPS5823793(A) 申请公布日期 1983.02.12
申请号 JP19820009568 申请日期 1982.01.26
申请人 HAYASHIBARA SEIBUTSU KAGAKU KENKYUSHO KK 发明人 SUGIMOTO KANAME
分类号 C12N15/02;A61K35/12;A61K38/16;A61P37/00;A61P43/00;C12P21/00;C12P21/02;C12R1/91 主分类号 C12N15/02
代理机构 代理人
主权项
地址