摘要 |
PURPOSE:Human-originating cells, which are capable of producing hTCGF, are proliferated in a warm-blood animal to produce the hTCGF in high efficiency. CONSTITUTION:Human-originating cells, which are capable of producing hTCGF, such as human peripheral hemocytes, are transplanted in a body of blood-warm animal other than human as young as possible. Or a difusion chamber provided with a porous filtration membrane that prevents animal cells from passing through is embedded in an animal body to effect the proliferation of the human cells as they are receiving nutrients from the animal body for 1-20 weeks. Thus, the number of the proliferated human-originating cells reaches 10<2>-10<7> or more times that of the initially transplanted cells, which corresponds to 10<1>- 10<6> times that of the cells, when they are proliferated in vitro in an enriched culture medium. |