发明名称 Isotonic monomer formulations
摘要 Application of a composition of matter comprising a solution of water in relatively nontoxic water-stable ethylenically unsaturated monomers, preferably methacrylate and/or acrylate and most preferably methacrylate monomers, which solution is substantially isotonic with normal physiological saline solution. As a further aspect of the invention, the compositions may be prepared by selecting ethylenically unsaturated monomers of varying hydrophilicity or water solubility, equilibrating each such monomer with water to form a two phase system and measuring the concentration of the monomer in the water-rich phase, preparing a mixture of monomers in equilibrium with water such that their cumulative concentration in the water phase is about 0.31 molar, and collecting the monomer-rich phase, which will be saturated with water and will also be isotonic with normal physiological saline.
申请公布号 US4373035(A) 申请公布日期 1983.02.08
申请号 US19810269067 申请日期 1981.06.01
申请人 AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION 发明人 BOWEN, RAFAEL L.
分类号 A61K6/00;A61K6/083;A61K6/10;A61L24/06;(IPC1-7):C08L33/14 主分类号 A61K6/00
代理机构 代理人
主权项
地址