AMINOBENZOIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS OR AS INTERMEDIATES

摘要

Aminobenzoic acid derivatives are disclosed of the general formual: (I) whreein R1 represents a hydrogen or halogen atom, R2 and R3 each represents alkyl, cycloalkyl, phenylalkyl or pyridyl, or together represent a cyclic imino group or one of the radicals R2 and R3 represents a hydrogen atom, A represnets a cycloalkylene group or an optionally substituted or interrupted alkylene group, X represents an oxygen atom or an imino group and Y represents a hydroxy or amino group, a halogen atom, an aminobenzoyloxy or aminobenzoic acid amido group or with the .alpha.- and .beta.-carbon atoms of the radical A represents an oxiranyl or1,3-dioxolanyl group, as well as their acid addition salts. These compounds exhibit valuable pharmacological properties. Besides a secretolytic and/or antitussive activity, they especially show an antiulcus activity. Moreover, they represent intermediates for thepreparation of compounds with an antiphlogistic activity.