PROCEDEU DE OBTINERE A UNOR ANTIBIOTICE MACROLIDE

摘要

Macrolides of formula (I): wherein R is hydrogen or acyl, and wherein Q is hydrogen or a mycarosyl group of formula: wherein R<1> is hydrogen or acyl; provided that when Q is hydrogen, R is acyl; can be prepared by the submerged aerobic cultivation of Streptomyces fradiae NRRL 12201 and are useful as intermediates in the preparation of other macrolides such as tylosin.