| 摘要 |
4-(Phenyl)piperidine compounds of the general formula I <IMAGE> in which R1 represents a radical of the formula <IMAGE> in which R3 denotes hydrogen or lower alkyl, Ph denotes a p-phenylene radical which is optionally substituted by lower alkyl, lower alkoxy, nitro and/or halogen, and R2 represents lower alkyl and R3 denotes hydrogen, with the proviso that R2 has at least two carbon atoms if Ph is unsubstituted and R3 denotes hydrogen, have antidepressant properties and can be used as antidepressant active compounds for drugs. The compounds of the formula I are prepared by subjecting a compound of the general formula <IMAGE> in which R1' denotes a radical <IMAGE> to, e.g. thermal, decarboxylation.
|
