发明名称 |
DIBENZ B,F OXEPIN AND DIBENZO B,F THIEPIN DERIVATIVES |
摘要 |
The invention provides dibenz [b, f] oxepin and dibenzo [b, f] thiepin derivatives of the formula …<CHEM>… wherein X is an oxygen or sulfur atom, each of R1 and R2 is a hydrogen atom or a methyl group, and R3 is a hydrogen atom or a 2-(2-hydroxyethoxy) ethyl group; provided that when R1 is a hydrogen …<CHEM>… atom, the group -CHCOOR3 is a group other than a I-carboxyethyl group, and when X is a sulfur atom, both R1 and R2 are methyl groups; …<??>and pharmaceutically acceptable salts of said compounds in which R3 is a hydrogen atom. Compositions of said compounds or salts and processes for their preparation are also provided. These compounds and salts thereof have excellent anti-inflammatory, analgesic and antipyretic activities. |
申请公布号 |
AU526739(B2) |
申请公布日期 |
1983.01.27 |
申请号 |
AU19790044303 |
申请日期 |
1979.02.16 |
申请人 |
DAINIPPON PHARMACEUTICAL CO.,LTD. |
发明人 |
HITOSHI UNO;YASUTAKA NAGAI;HIDEO NAKAMURA |
分类号 |
A61K31/335;A61P25/04;A61P29/00;C07C41/26;C07C43/295;C07C59/68;C07C65/34;C07D295/194;C07D313/14;C07D337/14;(IPC1-7):61K31/335;07C65/00;07C149/40;07D337/14;07D313/14;61K31/38 |
主分类号 |
A61K31/335 |
代理机构 |
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