摘要 |
<p>The preparation of synthetic erythrocytes by forming a mixture of phospholipid and stroma-free hemoglobin and passing this mixture under pressure of from 500 to 10,000 pounds per square inch through an orifice to thereby form synthetic erythrocytes which contain stroma-free hemoglobin within membranes of phospholipid material. Also, subjecting the synthetic erythrocytes so formed to lyophilization to convert the liquid crystal structure of the erythrocytes to anon-crystal liquid which is capable of reconstitution into its liquid crystal form. Also, the recirculation of stroma-free hemoglobin not encapsulated within phospholipid membranes to be introduced again along with other stroma-free hemoglobin into mixture with lipids.</p> |