ORGANOSILICON COUMPOUNDS FOR THE TREATMENT OF HYPERTENSION AND TUMORS

摘要

A novel medicament which is effective as an antihypertensive agent is proposed which contains, as its effective ingredient, an organosilicon compound represented by the general formula R3Si(CH2)nCOOH, where R denotes an alkyl group having from 1 to 6 carbon atoms and n is an integer from 1 to 5 inclusive, or a therapeutically acceptable salt thereof such as a salt with an alkali metal, e.g. sodium or potassium. The effectiveness of the compound, for example, 3-trimethylsilyl butyric acid as well as the sodium and potassium salts thereof is established by the animal test undertaken with hypertensive rats.